Reduced production of saliva during sleep.

In all people, no matter their age or state of oral health, the largest oral odor occurs after a prolonged period of reduced saliva flow, increasing the alkalinity oral (after fasting, during sleep) and abstinence from food and liquid. This is accentuated in cases with any type of periodontal inflammatory process. When there is no salivary fluid, the putrefaction of oral exfoliated epithelial cells and other detritus cause a little pleasant smell, which rapidly disappears after the resumption of normal salivary flow. When the whole saliva remains stagnant for 24 hours at 37 ° C, the formation of the odor coincided with the rise at three times the size of the odor generated by the initial number of organisms present in the sample taken recently. When there is little saliva was found in 20-100 times more organism’s gram positive, gram negative organisms in areas such as the marginal ridge, where they expect to happen salivary restraint, gram-negative organisms were found 10 times more than gram positive organisms.
It is not a surprise to find that the bacterial population ranged within the various micro-environments in the mouth. The stench is intrinsic easily produced by microorganisms in areas located inside the mouth, where it commonly occurs retention of saliva, such a bad smell does not occur in areas with abundant salivary flow. A change to a more acid pH or the presence of small amounts of glucose can affect the metabolism of oral flora in a way that results in the formation of final products painless. An acidic pH prevents the formation of metabolic products smelling inactivated enzymes that are required in the putrefaction of amino acids.